|
|
|
These carbonyl and hydroxyl oxygens have been proposed to facilitate the switch of the methyl group during catalysis 16 , 21 , 24 In addition, [lawyer articles](https://git.nosharpdistinction.com/johniehefner99/brayden2014/wiki/Aspartame-The-Style-That-Kills-Poisoning-And-Detox) tyrosine residues within the [lysine-binding clefts](https://app.photobucket.com/search?query=lysine-binding%20clefts) of SET7/9 (Tyr245 and Tyr305) and DIM-5 (Tyr178) hydrogen-bond to the lysine ε-amino group, [lawyer in my area](https://heealthy.com/question/goldie-hawn-and-kurt-russells-home-on-forbes-record-video/) aligning it for a methyltransfer with AdoMet (Determine 4b,c ). |