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Methylation been found on a spread of lysine residues in numerous histones: K4 (using the only-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, K20 [lawyers in my area](https://gitea.cloudfindtime.com/valliekbj8935) histone H4, K59 in the globular domain of histone H4 2 and K26 of histone H1B 3 A number of proteins responsible for the methylation of specific residues have been characterised, and all however considered one of these accommodates a SET domain |